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Date of Award
Spring 2025
Degree Name
Master of Medical Science (Physician Assistant)
Department
Physician Assistant; College of Health Sciences
First Advisor
Kevin Basile
Abstract
Lateral epicondylitis, also known as “tennis elbow”, is the inflammation or injury to the extensor tendons on the lateral aspect of the elbow, typically resulting from repetitive use. Current treatments include NSAIDs, corticosteroid injections, physical therapy, bracing and surgery (debridement, dry needling, etc.), however, long term relief is not always obtained from these therapeutic interventions. Platelet-Rich Plasma (PRP) is a regenerative therapy involving the injection of a mix of concentrated platelets, which promotes growth factors to the site of injury and may aid in healing and tissue repair1. Analyzing evidence from multiple studies reveals PRP can offer long-term pain relief and improved functional outcomes for patients with lateral epicondylitis (LE) in terms of strength and return to activity, especially when first-line conservative therapies prove unsuccessful. However, challenges such as high cost, lack of FDA regulation and variability in preparation methods remain. This article provides an overview of current PRP research, its clinical applications and ethical considerations to guide healthcare providers in the use of PRP and making evidence-based decisions.
Recommended Citation
Berdy, Katelyn E., "Platelet-Rich Plasma for Lateral Epicondylitis: Evaluating an Emerging Alternative" (2025). Capstone Showcase. 62.
https://scholarworks.arcadia.edu/showcase/2025/pa/62
Platelet-Rich Plasma for Lateral Epicondylitis: Evaluating an Emerging Alternative
Lateral epicondylitis, also known as “tennis elbow”, is the inflammation or injury to the extensor tendons on the lateral aspect of the elbow, typically resulting from repetitive use. Current treatments include NSAIDs, corticosteroid injections, physical therapy, bracing and surgery (debridement, dry needling, etc.), however, long term relief is not always obtained from these therapeutic interventions. Platelet-Rich Plasma (PRP) is a regenerative therapy involving the injection of a mix of concentrated platelets, which promotes growth factors to the site of injury and may aid in healing and tissue repair1. Analyzing evidence from multiple studies reveals PRP can offer long-term pain relief and improved functional outcomes for patients with lateral epicondylitis (LE) in terms of strength and return to activity, especially when first-line conservative therapies prove unsuccessful. However, challenges such as high cost, lack of FDA regulation and variability in preparation methods remain. This article provides an overview of current PRP research, its clinical applications and ethical considerations to guide healthcare providers in the use of PRP and making evidence-based decisions.