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Date of Award

Spring 2024

Degree Name

Master of Medical Science (Physician Assistant)

Department

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First Advisor

Jaime Shaffer

Second Advisor

Michelle Thal

Abstract

Premenstrual Dysphoric Disorder (PMDD) is a perimenstrual condition that has an effect on a person’s mood, and is characterized by irritability, anxiety, depression, and changes in behavior that occur the week prior to menses. Current treatment options for PMDD include selective serotonin reuptake inhibitors, hormonal therapy, surgery, and many others, however no one treatment alone stands to help all patients experiencing this disorder. The symptoms of PMDD cause dysfunction in the daily lives of the patients that it affects, which is why more research is indicated for better treatment options or supplemental therapy. Ashwagandha is a supplement that is currently thought to alleviate symptoms of anxiety and depression in those with diagnosable disorders. As anxiety and depression are two of the key features of PMDD, it seems reasonable to believe that Ashwagandha may be a valid treatment option for those with PMDD.

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Managing Premenstrual Dysphoric Disorder with Ashwagandha: Current Clinical Evidence and Potential Health Implications

Premenstrual Dysphoric Disorder (PMDD) is a perimenstrual condition that has an effect on a person’s mood, and is characterized by irritability, anxiety, depression, and changes in behavior that occur the week prior to menses. Current treatment options for PMDD include selective serotonin reuptake inhibitors, hormonal therapy, surgery, and many others, however no one treatment alone stands to help all patients experiencing this disorder. The symptoms of PMDD cause dysfunction in the daily lives of the patients that it affects, which is why more research is indicated for better treatment options or supplemental therapy. Ashwagandha is a supplement that is currently thought to alleviate symptoms of anxiety and depression in those with diagnosable disorders. As anxiety and depression are two of the key features of PMDD, it seems reasonable to believe that Ashwagandha may be a valid treatment option for those with PMDD.