Radical Prostatectomy vs. Radiation Therapy in the Treatment of Prostate Cancer

Date of Award

Spring 2023

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Elizabeth Masten

Abstract

Prostate cancer is the most common malignant neoplasm affecting men worldwide, and its prevalence has been steadily increasing due to more regular and advanced screening methods. Currently the two most effective and commonly used treatment modalities are radiation therapy and radical prostatectomy. With an estimated 1 in 7 men receiving a prostate cancer diagnosis in their lifetimes, it is incredibly important for providers to understand the benefits and risks of each modality, as well as their efficacy in relation to one another. Many patients and providers will naturally feel that radical prostatectomy provides better assurances of cure as the goal of the procedure is to remove the entire prostate, as opposed to radiating only neoplastic tissue. While this decision is sometimes driven by the “Get the cancer out of me” mentality, it is crucial to separate pathos and logos when evaluating the most efficacious and risk-appropriate course for treating this disease. This presentation evaluates up-to-date research on disease recurrence rates following radiation therapy and radical prostatectomy, as well as adverse effect rates associated with these modalities to enhance the current understanding of the most appropriate option for prostate cancer patients.

Additional Files

Capstone Poster.pptx (1003 kB)

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Radical Prostatectomy vs. Radiation Therapy in the Treatment of Prostate Cancer

Prostate cancer is the most common malignant neoplasm affecting men worldwide, and its prevalence has been steadily increasing due to more regular and advanced screening methods. Currently the two most effective and commonly used treatment modalities are radiation therapy and radical prostatectomy. With an estimated 1 in 7 men receiving a prostate cancer diagnosis in their lifetimes, it is incredibly important for providers to understand the benefits and risks of each modality, as well as their efficacy in relation to one another. Many patients and providers will naturally feel that radical prostatectomy provides better assurances of cure as the goal of the procedure is to remove the entire prostate, as opposed to radiating only neoplastic tissue. While this decision is sometimes driven by the “Get the cancer out of me” mentality, it is crucial to separate pathos and logos when evaluating the most efficacious and risk-appropriate course for treating this disease. This presentation evaluates up-to-date research on disease recurrence rates following radiation therapy and radical prostatectomy, as well as adverse effect rates associated with these modalities to enhance the current understanding of the most appropriate option for prostate cancer patients.