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Date of Award

Spring 2020

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Lisa Murphy

Abstract

Many adults suffering with knee pain due to osteoarthritis (OA) rely on intra-articular corticosteroids for pain management. Mesenchymal Stem Cells (MSC) intra-articular injections have emerged as an alternative treatment that may have less side effects and may alter disease progression. This review of literature seeks to compare efficacy of pain control of MSC injections compared to standard of care. More research is required however intra-articular MSC injections show statistically significant reductions in pain similar to corticosteroid injections.

Additional Files

MSC vs IAC.pdf (368 kB)

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Efficacy of Intra-articular Mesenchymal Stem Cell Injections Compared to Intra-articular Corticosteroids in Pain Control for Osteoarthritis of the Knee

Many adults suffering with knee pain due to osteoarthritis (OA) rely on intra-articular corticosteroids for pain management. Mesenchymal Stem Cells (MSC) intra-articular injections have emerged as an alternative treatment that may have less side effects and may alter disease progression. This review of literature seeks to compare efficacy of pain control of MSC injections compared to standard of care. More research is required however intra-articular MSC injections show statistically significant reductions in pain similar to corticosteroid injections.