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Date of Award

Spring 2020

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Renee Langstaff, MSPAS, PA-C

Abstract

Atherosclerotic plaque build up begins during childhood, increasing a patients risk for developing cardiovascular disease (CVD). Hyperlipidemia (HLD) is one of the major risk factors for developing atherosclerosis, along with decreased exercise, poor diet, obesity, high blood pressure, smoking, age, and family history. Standard treatment for HLD is lifestyle changes in diet and exercise, and statin use. However, statin use has been questioned in children as it could interfere with their growth and development. While statins are used in children with familial HLD, this meta-analysis will look at the effectiveness of implementing diet and exercise lifestyle changes compared to current statin use in treating pediatric patients, ages 8-18 years old, with LDL levels greater than 130 mg/dl.

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Efficacy of lifestyle changes compared to statin use in controlling hyperlipidemia in pediatric patients ages 8-18 years old

Atherosclerotic plaque build up begins during childhood, increasing a patients risk for developing cardiovascular disease (CVD). Hyperlipidemia (HLD) is one of the major risk factors for developing atherosclerosis, along with decreased exercise, poor diet, obesity, high blood pressure, smoking, age, and family history. Standard treatment for HLD is lifestyle changes in diet and exercise, and statin use. However, statin use has been questioned in children as it could interfere with their growth and development. While statins are used in children with familial HLD, this meta-analysis will look at the effectiveness of implementing diet and exercise lifestyle changes compared to current statin use in treating pediatric patients, ages 8-18 years old, with LDL levels greater than 130 mg/dl.