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Date of Award
Spring 2025
Degree Name
Master of Medical Science (Physician Assistant)
Department
Physician Assistant; College of Health Sciences
First Advisor
Kelly Moss
Abstract
Kawasaki disease, also called mucocutaneous lymph node syndrome, is an infectious condition causing inflammation of the walls of small to medium sized blood vessels. It is primarily seen in children under the age of 5 in which it affects the arteries supplying blood to the heart. Because of this, Kawasaki disease is the leading cause of acquired heart disease in children in the United States and can cause serious complications including coronary artery dilations and aneurysms. Due to the similarities in presentation of Kawasaki disease to other infectious disorders, (such as streptococcal pharyngitis, measles, and rubella), it can be difficult to diagnose right away. To avoid the risk of permanent heart complications, Kawasaki disease must be treated as promptly as possible. Therefore, it is essential for providers to be aware of the approach to early diagnosis, treatment, and management of Kawasaki disease. This article aims to provide evidence-based guidelines to achieve early and prompt diagnosis of Kawasaki disease in order to prevent long-term heart defects and improve overall quality of life in children with the disease.
Recommended Citation
Schlaich, Lindsay, "Approach to Differentiating and Diagnosing Kawasaki Disease in Children" (2025). Capstone Showcase. 13.
https://scholarworks.arcadia.edu/showcase/2025/pa/13
Approach to Differentiating and Diagnosing Kawasaki Disease in Children
Kawasaki disease, also called mucocutaneous lymph node syndrome, is an infectious condition causing inflammation of the walls of small to medium sized blood vessels. It is primarily seen in children under the age of 5 in which it affects the arteries supplying blood to the heart. Because of this, Kawasaki disease is the leading cause of acquired heart disease in children in the United States and can cause serious complications including coronary artery dilations and aneurysms. Due to the similarities in presentation of Kawasaki disease to other infectious disorders, (such as streptococcal pharyngitis, measles, and rubella), it can be difficult to diagnose right away. To avoid the risk of permanent heart complications, Kawasaki disease must be treated as promptly as possible. Therefore, it is essential for providers to be aware of the approach to early diagnosis, treatment, and management of Kawasaki disease. This article aims to provide evidence-based guidelines to achieve early and prompt diagnosis of Kawasaki disease in order to prevent long-term heart defects and improve overall quality of life in children with the disease.