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Date of Award
Spring 2025
Degree Name
Master of Medical Science (Physician Assistant)
Department
Physician Assistant; College of Health Sciences
First Advisor
Jessica Hammerman
Abstract
Warts can be irritating for patients and healthcare providers by causing embarrassment, discomfort, and frustration due to resistance and recurrence. Warts have been around for thousands of years yet there still is no clear definitive therapy. This article provides an overarching review of the pathophysiology, risk factors, clinical manifestations, diagnostics, prevention, and complications of viral warts. Common management options used for the treatment of viral warts are discussed to help expand providers’ awareness of the available options. Finally, the article strives to educate providers and patients on cimetidine as a novel treatment option for warts. Most people are only familiar with cimetidine as a treatment for peptic ulcer disease, heartburn, and reflux. However, cimetidine is a Histamine-2 (H2) receptor antagonist with immunomodulatory effects that have also displayed encouraging results in wart remission for patients with multiple or refractory warts.
Recommended Citation
Tyler, Summer, "Warts, Their Treatment, and the Role of Cimetidine: Exploring Therapeutic Approaches and Efficacy" (2025). Capstone Showcase. 11.
https://scholarworks.arcadia.edu/showcase/2025/pa/11
Warts, Their Treatment, and the Role of Cimetidine: Exploring Therapeutic Approaches and Efficacy
Warts can be irritating for patients and healthcare providers by causing embarrassment, discomfort, and frustration due to resistance and recurrence. Warts have been around for thousands of years yet there still is no clear definitive therapy. This article provides an overarching review of the pathophysiology, risk factors, clinical manifestations, diagnostics, prevention, and complications of viral warts. Common management options used for the treatment of viral warts are discussed to help expand providers’ awareness of the available options. Finally, the article strives to educate providers and patients on cimetidine as a novel treatment option for warts. Most people are only familiar with cimetidine as a treatment for peptic ulcer disease, heartburn, and reflux. However, cimetidine is a Histamine-2 (H2) receptor antagonist with immunomodulatory effects that have also displayed encouraging results in wart remission for patients with multiple or refractory warts.