Narcolepsy Recognition and Management
Date of Award
Spring 2024
Degree Name
Master of Medical Science (Physician Assistant)
Department
Physician Assistant; College of Health Sciences
First Advisor
Timothy Besse
Abstract
Narcolepsy is a chronic neurodegenerative condition with variable clinical presentation and severity in which it affects patients. Typical case presentation includes EDS, cataplexy, sleep attacks and paralysis which have devastating psychosocial and mental health consequences. The pathophysiology of NT1 is understood to be caused by a deficit in orexin. Currently, PSG and MSLT are the most widely employed diagnostic tools, in addition to CSF orexin levels. Treatment options are plenty, most commonly being the stimulant modafinil and adding sodium oxybate to target cataplexy.
Recommended Citation
Shah, Alisha, "Narcolepsy Recognition and Management" (2024). Capstone Showcase. 78.
https://scholarworks.arcadia.edu/showcase/2024/pa/78
Narcolepsy Recognition and Management
Narcolepsy is a chronic neurodegenerative condition with variable clinical presentation and severity in which it affects patients. Typical case presentation includes EDS, cataplexy, sleep attacks and paralysis which have devastating psychosocial and mental health consequences. The pathophysiology of NT1 is understood to be caused by a deficit in orexin. Currently, PSG and MSLT are the most widely employed diagnostic tools, in addition to CSF orexin levels. Treatment options are plenty, most commonly being the stimulant modafinil and adding sodium oxybate to target cataplexy.