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Date of Award

Spring 2023

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Elizabeth Masten

Abstract

Osteoarthritis (OA) is a chronic degenerative disease that causes functional impairment and pain to a large population of people worldwide. While multiple joints can be affected by OA, weight-bearing joints are the most common. Particularly, the knee joint makes up approximately 41% of all OA cases.There are currently many ways to treat the symptoms of knee OA including pharmacological agents, intra-articular injections, and surgical procedures. The goals of these treatment options are to alleviate pain and improve the functionality of the knee. Various research is currently being conducted to find a more effective treatment option to delay the need for surgical interventions, as such practices can result in more medical complications. This presentation focuses on the non-surgical treatment for knee OA and will compare the clinical outcomes of Viscosupplementation with hyaluronic acid and platelet-rich plasma (PRP), which is a recently developed treatment option for OA.

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Nonsurgical Treatment of Knee Osteoarthritis: Platelet Rich Plasma vs Viscosupplementation

Osteoarthritis (OA) is a chronic degenerative disease that causes functional impairment and pain to a large population of people worldwide. While multiple joints can be affected by OA, weight-bearing joints are the most common. Particularly, the knee joint makes up approximately 41% of all OA cases.There are currently many ways to treat the symptoms of knee OA including pharmacological agents, intra-articular injections, and surgical procedures. The goals of these treatment options are to alleviate pain and improve the functionality of the knee. Various research is currently being conducted to find a more effective treatment option to delay the need for surgical interventions, as such practices can result in more medical complications. This presentation focuses on the non-surgical treatment for knee OA and will compare the clinical outcomes of Viscosupplementation with hyaluronic acid and platelet-rich plasma (PRP), which is a recently developed treatment option for OA.