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Date of Award

Spring 2023

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Diana Hawthorne, MSPAS, PA-C

Abstract

Hypertension is a chronic disease of the cardiovascular system that is highly prevalent amongst the African American community affecting over 1/3 Black individuals. Uncontrolled hypertension can lead to severe end-organ dysfunction such as cerebrovascular accidents and kidney damage. The current standard of care includes lifestyle modifications and pharmacologic therapy, though current recommendations advise against the use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) as monotherapy in Black patients. This review analyzes the efficacy of this guideline and the importance of the reevaluation of the efficacy of race-based medicine.

Additional Files

HTN in AA Poster Presentation.pptx (1002 kB)

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Efficacy of Current Hypertension Guidelines in African Americans

Hypertension is a chronic disease of the cardiovascular system that is highly prevalent amongst the African American community affecting over 1/3 Black individuals. Uncontrolled hypertension can lead to severe end-organ dysfunction such as cerebrovascular accidents and kidney damage. The current standard of care includes lifestyle modifications and pharmacologic therapy, though current recommendations advise against the use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) as monotherapy in Black patients. This review analyzes the efficacy of this guideline and the importance of the reevaluation of the efficacy of race-based medicine.