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Date of Award
Spring 2023
Degree Name
Master of Medical Science (Physician Assistant)
Department
Physician Assistant; College of Health Sciences
First Advisor
Jamie Shaffer
Abstract
Treatment resistant depression(TRD) is something which has yet to be assigned a standard definition across different practice guidelines, textbooks, and clinical trials. Definitions have ranged from failure to respond to one treatment of antidepressant monotherapy to depression that necessitates electroconvulsive therapy(ECT). In light of this lack of consensus, this article will aim to help the clinician better identify patients suffering from TRD. Coupled with the spate of novel approaches that have been implemented in recent years to address TRD including transcranial magnetic stimulation(TMS) and ketamine use, a review of the newest evidence for treating TRD can better help the clinician manage this vulnerable patient population.
Recommended Citation
Smith, Sean, "Evaluating efficacy of different therapies for treatment resistant depression" (2023). Capstone Showcase. 101.
https://scholarworks.arcadia.edu/showcase/2023/pa/101
Evaluating efficacy of different therapies for treatment resistant depression
Treatment resistant depression(TRD) is something which has yet to be assigned a standard definition across different practice guidelines, textbooks, and clinical trials. Definitions have ranged from failure to respond to one treatment of antidepressant monotherapy to depression that necessitates electroconvulsive therapy(ECT). In light of this lack of consensus, this article will aim to help the clinician better identify patients suffering from TRD. Coupled with the spate of novel approaches that have been implemented in recent years to address TRD including transcranial magnetic stimulation(TMS) and ketamine use, a review of the newest evidence for treating TRD can better help the clinician manage this vulnerable patient population.