Clinical Fertility Management in Polycystic Ovarian Syndrome Patients

Date of Award

Spring 2022

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Kimberly Erikson, PA-C

Abstract

Polycystic Ovarian Syndrome affects 5-20% of women of reproductive age in the United States¹. It is a complex endocrine disorder that affects female fertility, insulin resistance, and produces symptoms of hyperandrogenism including cystic acne, hirsutism, and abdominal weight gain. Patients with PCOS who want to conceive should be treated with a multi-layered approach which can include lifestyle modification, pharmaceutical therapy, or surgery. Lifestyle modification includes weight loss through physical activity and dietary modification as well as focus on mental health. Pharmaceutical therapies include clomiphene citrate, letrozole, or gonadotropin therapy Finally, surgical intervention can be used as a third line treatment including ovarian drilling and IVF.

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Buzzetti Capstone Presentation.pptx.pdf (802 kB)

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Clinical Fertility Management in Polycystic Ovarian Syndrome Patients

Polycystic Ovarian Syndrome affects 5-20% of women of reproductive age in the United States¹. It is a complex endocrine disorder that affects female fertility, insulin resistance, and produces symptoms of hyperandrogenism including cystic acne, hirsutism, and abdominal weight gain. Patients with PCOS who want to conceive should be treated with a multi-layered approach which can include lifestyle modification, pharmaceutical therapy, or surgery. Lifestyle modification includes weight loss through physical activity and dietary modification as well as focus on mental health. Pharmaceutical therapies include clomiphene citrate, letrozole, or gonadotropin therapy Finally, surgical intervention can be used as a third line treatment including ovarian drilling and IVF.