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Date of Award

Spring 2021

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Elizabeth Masten

Abstract

Clinicians need more evidence-based medical guidance into which medications better treat patients predominantly experiencing a specific PTSD symptom cluster. Based on the review of 6 research articles, both venlafaxine and sertraline show statistically significant improvements in reexperiencing/intrusion PTSD symptoms when compared to baseline and placebo. These results are generalizable across a broad population due to the studies’ sample diversity. Furthermore, more research is needed into other SSRIs and SNRIs to treat other PTSD symptom clusters.

Additional Files

Samantha Rodriguez Capstone Poster.pdf (471 kB)

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Efficacy of Sertraline (Zoloft) Compared to Venlafaxine (Effexor) in Improving Reexperiencing/Intrusion Symptoms in Adults with PTSD

Clinicians need more evidence-based medical guidance into which medications better treat patients predominantly experiencing a specific PTSD symptom cluster. Based on the review of 6 research articles, both venlafaxine and sertraline show statistically significant improvements in reexperiencing/intrusion PTSD symptoms when compared to baseline and placebo. These results are generalizable across a broad population due to the studies’ sample diversity. Furthermore, more research is needed into other SSRIs and SNRIs to treat other PTSD symptom clusters.