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Date of Award
Spring 2021
Degree Name
Master of Medical Science (Physician Assistant)
Department
Physician Assistant; College of Health Sciences
First Advisor
Elizabeth Masten
Abstract
Clinicians need more evidence-based medical guidance into which medications better treat patients predominantly experiencing a specific PTSD symptom cluster. Based on the review of 6 research articles, both venlafaxine and sertraline show statistically significant improvements in reexperiencing/intrusion PTSD symptoms when compared to baseline and placebo. These results are generalizable across a broad population due to the studies’ sample diversity. Furthermore, more research is needed into other SSRIs and SNRIs to treat other PTSD symptom clusters.
Recommended Citation
Rodriguez, Samantha N., "Efficacy of Sertraline (Zoloft) Compared to Venlafaxine (Effexor) in Improving Reexperiencing/Intrusion Symptoms in Adults with PTSD" (2021). Capstone Showcase. 84.
https://scholarworks.arcadia.edu/showcase/2021/pa/84
Efficacy of Sertraline (Zoloft) Compared to Venlafaxine (Effexor) in Improving Reexperiencing/Intrusion Symptoms in Adults with PTSD
Clinicians need more evidence-based medical guidance into which medications better treat patients predominantly experiencing a specific PTSD symptom cluster. Based on the review of 6 research articles, both venlafaxine and sertraline show statistically significant improvements in reexperiencing/intrusion PTSD symptoms when compared to baseline and placebo. These results are generalizable across a broad population due to the studies’ sample diversity. Furthermore, more research is needed into other SSRIs and SNRIs to treat other PTSD symptom clusters.