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Date of Award

Spring 2021

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Kerry Gregory

Second Advisor

ToriAnne Yetter

Abstract

Parkinson’s Disease (PD) is a neurodegenerative disorder that causes both motor and non-motor symptoms. Although there is no cure for PD, treatment is focused on slowing down the progression with the first line drug being levodopa. Levodopa can be ineffective with continued use, so other drugs such as cannabis are being trialed to see how they affect the patient’s quality of life. The objective of this study was to determine the efficacy of cannabis/cannabidiol in patients with early stage, tremor dominant, Parkinson’s disease (PD) compared to L-dopa.

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Cannabis in the treatment of tremor dominant Parkinson's Disease

Parkinson’s Disease (PD) is a neurodegenerative disorder that causes both motor and non-motor symptoms. Although there is no cure for PD, treatment is focused on slowing down the progression with the first line drug being levodopa. Levodopa can be ineffective with continued use, so other drugs such as cannabis are being trialed to see how they affect the patient’s quality of life. The objective of this study was to determine the efficacy of cannabis/cannabidiol in patients with early stage, tremor dominant, Parkinson’s disease (PD) compared to L-dopa.