Bone marrow transplantation from haploidentical donors compared to patients receiving bone marrow transplantation from matched unrelated donors

Date of Award

Spring 2021

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Shannon Diallo, PA-C

Abstract

Traditionally the treatment for hematologic malignancy, including adults (>18 years old) has been a bone marrow transplant using either a matched related donor, such as a sibling, or matched unrelated donor using HLA typing. Only 30% of patients have a family member eligible to donate their bone marrow with the remaining 70% of patients left to find an HLA match through the registry¹. Additionally, ethnic minorities in particular have an exceptionally challenging search process for an HLA match. Haploidentical bone marrow transplants would provide a treatment option for numerous patients that have children or parents eligible to donate their bone marrow.

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Additional Files

References_Purang.pdf (75 kB)
Poster_Purang.pptx.pdf (351 kB)
purang capstone presentation.mp4 (24797 kB)

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Bone marrow transplantation from haploidentical donors compared to patients receiving bone marrow transplantation from matched unrelated donors

Traditionally the treatment for hematologic malignancy, including adults (>18 years old) has been a bone marrow transplant using either a matched related donor, such as a sibling, or matched unrelated donor using HLA typing. Only 30% of patients have a family member eligible to donate their bone marrow with the remaining 70% of patients left to find an HLA match through the registry¹. Additionally, ethnic minorities in particular have an exceptionally challenging search process for an HLA match. Haploidentical bone marrow transplants would provide a treatment option for numerous patients that have children or parents eligible to donate their bone marrow.