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Date of Award

Spring 2025

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Timothy Besse

Abstract

Cardiac amyloidosis (CA) is thought of as a rare cause of heart failure, although underdiagnosis makes its true prevalence difficult to discern. Advances in diagnosis have revealed that CA is likely more prevalent than once previously believed. Despite the advances in treatment for cardiac amyloidosis, prognosis remains poor. Early recognition of “red flags” reduces delays in diagnosis and treatment. Additionally, as incidence of CA increases, clinicians must understand the treatment of CA and how it differs from other forms of heart failure. This CME emphasizes different epidemiological features and “red flags” that may alert a clinician to screen for cardiac amyloidosis. It will then discuss the diagnostic workup and treatment for CA and its comorbidities.

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Cardiac Amyloidosis: An Underdiagnosed Cause of Heart Failure

Cardiac amyloidosis (CA) is thought of as a rare cause of heart failure, although underdiagnosis makes its true prevalence difficult to discern. Advances in diagnosis have revealed that CA is likely more prevalent than once previously believed. Despite the advances in treatment for cardiac amyloidosis, prognosis remains poor. Early recognition of “red flags” reduces delays in diagnosis and treatment. Additionally, as incidence of CA increases, clinicians must understand the treatment of CA and how it differs from other forms of heart failure. This CME emphasizes different epidemiological features and “red flags” that may alert a clinician to screen for cardiac amyloidosis. It will then discuss the diagnostic workup and treatment for CA and its comorbidities.