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Date of Award
Spring 2020
Degree Name
Master of Medical Science (Physician Assistant)
Department
Physician Assistant; College of Health Sciences
First Advisor
Amanda Seymour PA-C
Abstract
Acute kidney injury (AKI) is a life-threatening condition and is especially dangerous in the vulnerable population of newborns. AKI is currently detected using the gold standard biomarker serum creatinine. Due to various disadvantages of creatinine when used in the neonatal population, it has been determined a suboptimal indicator of AKI. Cystatin C is a newly researched renal biomarker that is being considered for the assessment of neonatal kidney function. Therefore, this review analyzes the accuracy of cystatin C for detecting AKI in preterm and term newborns compared to the standard biomarker, creatinine.
Recommended Citation
Torrisi, Alexandria, "The Accuracy of Cystatin C in the Detection of Kidney Injury in Newborns" (2020). Capstone Showcase. 92.
https://scholarworks.arcadia.edu/showcase/2020/pa/92
The Accuracy of Cystatin C in the Detection of Kidney Injury in Newborns
Acute kidney injury (AKI) is a life-threatening condition and is especially dangerous in the vulnerable population of newborns. AKI is currently detected using the gold standard biomarker serum creatinine. Due to various disadvantages of creatinine when used in the neonatal population, it has been determined a suboptimal indicator of AKI. Cystatin C is a newly researched renal biomarker that is being considered for the assessment of neonatal kidney function. Therefore, this review analyzes the accuracy of cystatin C for detecting AKI in preterm and term newborns compared to the standard biomarker, creatinine.